New Delhi, June 7
Australian researchers have pioneered a new artificial intelligence (AI)-powered tool to assess the risk of developing type 1 diabetes (T1D).
The tool, developed by researchers at Western Sydney University, predicts treatment responses, potentially changing how the disease is diagnosed and managed.
The tool utilises an innovative risk score -- Dynamic Risk Score (DRS4C) which can classify individuals as having or not having T1D.
It is based on microRNAs -- small RNA molecules measured from blood -- to help accurately capture the changing risk of T1D.
"T1D risk prediction is timely, with therapies that can delay T1D progression becoming recognised and available. Since early-onset T1D before the age of 10 years is particularly aggressive and linked to up to 16 years of reduced life expectancy, accurately predicting progression gives doctors a powerful tool to intervene sooner," said Professor Anand Hardikar, lead investigator from the University's School of Medicine and Translational Health Research Institute.
In their article published in the journal Nature Medicine, the research analysed molecular data in 5,983 study samples from participants across India, Australia, Canada, Denmark, Hong Kong, New Zealand, and the US, to develop DRS4C.