Health

Diabetes may raise infection, blood clot risk post knee replacement surgery: Study

July 10, 2025

New Delhi, July 10

Diabetes may not only lead to joint pain that can severely damage your knee but also increase the risk of infections and blood clots after knee replacement surgery, according to a new study led by Indian researchers.

More than half of people with diabetes have coexisting arthropathy -- disease or condition affecting a joint -- and may need a hip or knee arthroplasty (joint replacement surgery) in the future.

The study led by researchers from the Vardhman Medical College & Safdarjung Hospital, New Delhi, showed that diabetes is a significant risk factor for joint infection following total knee arthroplasty (TKA) -- a popular and effective surgery for patients with advanced knee arthritis.

Deep vein thrombosis (DVT) or blood clots is another crucial postoperative complication after TKA, which may also cause pulmonary embolism -- a blood clot causing a blockage in pulmonary arteries in the lungs.

The condition can result in increased morbidity and mortality.

“The presence of diabetes significantly impacts post-TKA outcomes, leading to higher complication rates and negatively affecting physical function and quality of life,” said the researchers, including from Indraprastha Apollo Hospitals and Fortis C-Doc Hospital.

“Insulin-treated diabetics face 60 per cent higher perioperative adverse events. Poor sugar control around TKA surgery worsens outcomes,” they added, in the paper published in the Journal of Orthopaedics.

 

 

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