A team of scientists at the Institute of Advanced Study in Science and Technology (IASST), an autonomous institute of the Department of Science and Technology (DST), has found drugs with potential to treat neurodegenerative disorders -- a major global health challenge.

In the study, published in the Journal Drug Discovery Today, the team highlighted the potential of peptidomimetics to treat neurodegenerative diseases, like Alzheimer's disease, Parkinson's disease, by promoting neuronal growth and survival.

Peptidomimetic drugs -- or synthetic molecules that mimic the structure of natural proteins -- can be repurposed to provide an effective therapeutic strategy to treat neurodegenerative diseases by promoting neuronal growth and survival.

Manchester City will honour Kevin De Bruyne’s incredible decade of service to the Club by commissioning a special statue celebrating the midfielder’s magnificent Etihad career

It was was confirmed immediately after Tuesday night’s penultimate Premier League clash of the 2024/25 season at home to Bournemouth, which marked the 33-year-old’s final Etihad appearance for the Club.

De Bruyne revealed how proud and honoured he was at being afforded such a special tribute in the form of a statue.

"It means I will always be part of this club. Whenever I come back with family and friends, I will be able to see myself so I will always be here," De Bruyne said.

After a success laden 10 years at City, during which time he played more than 400 games, helping the Club win 19 major trophies, De Bruyne will be moving on in the summer.

Actor Ankit Siwach’s latest film, “Madam Driver”, has earned a special spot at the New York Indian Film Festival (NYIFF), where it will be showcased alongside works by acclaimed talents such as Nawazuddin Siddiqui, Manoj Bajpayee and Neena Gupta.

Sharing his excitement, Ankit, who is currently seen in the series “Kull”, said: “I was overwhelmed, very happy. The director, Indrajeet sir, the entire team, and I are all very happy that Madam Driver is being screened at the New York Indian Film Festival.”

The film, described as an experimental slice-of-life drama, stands out for its unconventional approach.

Despite weathering effects precipitated by global upheavals, Indian economy stays largely resilient and is projected to clock a GDP growth around 6.4-6.5 per cent in Q4 FY25, an SBI report said on Wednesday.

To estimate GDP statistically, the State Bank of India’s Economic Research Department has built a ‘Nowcasting Model’ with 36 high frequency indicators associated with industry activity, service activity, and global economy.

The model uses the dynamic factor model to estimate the common or representative or latent factor of all the high frequency indicators from Q4 of FY13 to Q2 of FY23.

“As per our ‘Nowcasting Model’, the forecasted GDP growth for Q4 FY25 should come around 6.4-6.5 per cent,” said Dr Soumya Kanti Ghosh, Group Chief Economic Advisor, SBI.

Veteran Bollywood actor Anupam Kher has expressed heartfelt gratitude to the Cannes Film Festival for the warm reception of his upcoming film “Tanvi The Great” and said he had a wonderful experience. He looks forward to returning with another film, either as an actor or director.

Anupam shared a video along with Pallavi Joshi, Boman Irani and debutante Shubhangi Dutt featuring in it.

Anupam is heard saying: “Hello, Cannes. Thank you so much for such a brilliant, amazing, heartwarming reception to our film Tanvi The Great. Thank you so much. I'm very happy and what a great festival it is. The film was received with love and warmth.”

“It touched the heart of everybody and thank you. We'll see you again with another film either as an actor or as a director. I would love to come back but I had a great time. We had a lovely time and it was brilliant.”

Anupam shared that the cast is now on their way to the London premiere of the film.

Selhurst Park completed an unforgettable 100th-anniversary season and bade farewell to one of its favourite sons Joel Ward, as Palace came out on top of a six-goal thriller to set a new Premier League points record – little over 72 hours after winning the FA Cup.

Eddie Nketiah scored twice as Crystal Palace celebrated their FA Cup triumph with a thrilling 4-2 victory over Wolverhampton Wanderers.

Ward, on his 364th Crystal Palace appearance, some 13 years after his debut, was handed the captain’s armband and his first Premier League start of the season in his final home match at Selhurst Park.

Emmanuel Agbadou headed Wolves in front midway through the first half. That woke the hosts up, though, and Nketiah scored twice in the space of five first-half minutes to turn the match around.

Maharashtra has reported two Covid-related deaths since January this year, the state health department has said, adding that the two were patients with comorbidities.

The department, late Tuesday night, stated that both deaths were reported from Mumbai and involved patients with comorbidities (simultaneous presence of two or more medical conditions in a person). One of the deceased had nephrotic syndrome with hypocalcemia seizure, while the other was a cancer patient.

According to the health department, a total of 6,066 swab samples have been examined for coronavirus since January, of which 106 tested positive for the infectious disease. Of these, 101 were from Mumbai and the remaining from Pune, Thane, and Kolhapur. Currently, 52 patients are undergoing treatment for mild symptoms, while 16 are being treated at hospitals.

"A spike in Covid-19 cases is not only being seen in Maharashtra, but also in other states and even other countries," said the health department release.

The Gemini app now has over 400 million monthly active users and we are seeing strong growth and engagement particularly with the 2.5 series of AI models, Sundar Pichai, CEO of Google and Alphabet, has said.

Over seven million developers are building with Gemini, five times more than this time last year, and Gemini usage on Vertex AI is up 40 times, said Pichai during the ‘Google I/O 2025’ conference in the US.

“For those using 2.5 Pro in the Gemini app, usage has gone up 45 per cent,” he informed.

This time last year, “we were processing 9.7 trillion tokens a month across our products and APIs. Now, we’re processing over 480 trillion — that’s 50 times more”, Pichai added.

He further stated that what all this progress means is that “we’re in a new phase of the AI platform shift, where decades of research are now becoming reality for people, businesses and communities all over the world”.

The Indian benchmark indices opened higher on Wednesday amid mixed global cues as buying was seen in the pharma, auto, PSU bank and financial service sectors in the early trade.

At around 9.35 am, Sensex was trading 296.53 points or 0.37 per cent up at 81,482.97 while the Nifty added 88.90 point or 0.36 per cent at 24,772.80

Nifty Bank was up 98.55 points or 0.18 per cent at 54,975.90. The Nifty Midcap 100 index was trading at 56,028.55 after declining 154.10 points or 0.27 per cent. Nifty Smallcap 100 index was at 17,419.35 after dropping 63.65 points or 0.36 per cent.

According to analysts, Indian equity benchmarks declined sharply on Tuesday amid reports of increasing COVID-19 cases in Southeast Asian countries, like Singapore and Hong Kong.

The Gujarat Anti-Terrorism Squad (ATS) has arrested a suspect from Nadiad for alleged involvement in anti-national cyber activities.

The accused, identified as Jasim Ansari, has been taken into custody along with his associate, both suspected to be part of a broader cyber conspiracy.

According to ATS sources, the duo was allegedly involved in an attempt to target Indian government websites during 'Operation Sindoor'.

The suspects are accused of associating with anti-India groups with the intent to disrupt the official digital infrastructure.

Among the sites targeted was the Aadhaar card portal, which they allegedly attempted to hack. Investigators revealed that both accused are matriculation-level passouts who reportedly learned hacking through YouTube tutorials and other online platforms.