Health

Researchers find novel genes linked to rare childhood diarrhoea

Researchers find novel genes linked to rare childhood diarrhoea

A team of Canadian researchers has identified three novel genes linked to rare childhood diarrhoea.

The rare condition called CODE (congenital diarrhoea and enteropathies) disrupts the function of cells in the intestine, causing diarrhoea. It also prevents infants from absorbing the nutrients they need to grow and thrive.

The team from The Hospital for Sick Children (SickKids) conducted genome sequencing on 129 infants with suspected CODE.

The scientists characterised the function of novel CODE genes using advanced computational methods and zebrafish models

The analysis was remarkably successful, providing a diagnosis for 48 per cent of cases.

Experts welcome US reciprocal tariff exemption on pharma, call to boost domestic manufacturing

Experts welcome US reciprocal tariff exemption on pharma, call to boost domestic manufacturing

Industry experts on Thursday welcomed the exemption of Indian pharmaceutical exports from Trump’s reciprocal tariffs while also stressing the need to strengthen domestic manufacturing.

The experts cited the importance of the cost-effective and life-saving Indian generic medicines as the reason for the exemption.

The White House factsheet issued on Wednesday after US President Donald Trump’s announcement of 26 per cent reciprocal tariffs on imports from India said that pharmaceuticals were exempt.

Indian drugs, especially the generics, help hold down the costs of the US healthcare system, which is already one of the most expensive in the world.

Cyanocobalamin safe, Vitamin B12 deficiency may impact brain, joints, skin health: Experts

Cyanocobalamin safe, Vitamin B12 deficiency may impact brain, joints, skin health: Experts

Amid social media debate on Cyanocobalamin, a synthetic form of Vitamin B12, being toxic for humans, experts on Wednesday deemed Cyanocobalamin safe, and stressed the need to not miss the key vitamin linked to the brain, joints, and skin health.

A recent viral post on social media has raised alarm over the use of cyanocobalamin in Vitamin B12 supplements. The post claims that it is harmful due to its breakdown into cyanide -- a toxic substance -- and suggests using Methylcobalam instead. Methylcobalamin is a natural form of vitamin B12 and contains a methyl group.

Even as the post went viral, it raised several concerns, especially as consumption of Vitamin B12 is high in India.

Ethiopia launches cholera vaccination for 1 million at-risk people

Ethiopia launches cholera vaccination for 1 million at-risk people

The Ethiopian government has launched a cholera vaccination campaign in the southwestern part of the country, targeting about one million people at risk.

In a statement issued on Sunday, the Ethiopian Ministry of Health said the vaccination will be conducted in all zones of the country's Gambella Region and refugee camps during the coming week.

It came as the World Health Organisation (WHO) and various other humanitarian agencies called for concerted efforts to contain the "rapidly spreading" cholera outbreak across the Gambella Region, bordering South Sudan.

Ethiopian Minister of Health Mekdes Daba, addressing the launch event, said that in addition to expanding access to cholera vaccines, maintaining environmental and personal hygiene are essential proactive measures to prevent cholera outbreaks.

New AI algorithm to predict risk of cardiovascular events, heart-related death

New AI algorithm to predict risk of cardiovascular events, heart-related death

A team of researchers in South Korea has developed a novel artificial intelligence (AI)-based algorithm that uses electrocardiograph (ECG)2 data to predict the risk of cardiovascular events, and heart-related death.

To create the algorithm, the team from Inha University Hospital analysed standard 12-lead electrocardiograph (ECG)2 data taken from almost half a million cases.

The novel algorithm can identify people most at risk of cardiovascular events and mortality by predicting the biological age of the heart, which is based on how the heart functions.

For example, a person who is 50 but has poor heart health could have a biological heart age of 60, while someone aged 50 with optimal heart health could have a biological heart age of 40.

Screen use during bedtime may raise your risk of insomnia by 59pc: Study

Screen use during bedtime may raise your risk of insomnia by 59pc: Study

Love to scroll your phone while in bed? Scientists have found that using a screen in bed can drive your risk of insomnia by 59 per cent.

While sleep is critical to mental and physical health, an increasing number of people are accustomed to using screens in bed. The study by researchers from the Norwegian Institute of Public Health in Norway showed it may be associated with poor sleep.

While social media is seen to be more associated with poorer sleep because of its interactive nature and potential for emotional stimulation, a survey of 45,202 young adults, aged between 18-28 years old, in Norway showed that the type of screen activity did not matter.

"We found no significant differences between social media and other screen activities, suggesting that screen use itself is the key factor in sleep disruption -- likely due to time displacement, where screen use delays sleep by taking up time that would otherwise be spent resting," said lead author Dr. Gunnhild Johnsen Hjetland, from the Institute.

South Korean medical students’ deadline to resume classes expires on Monday

South Korean medical students’ deadline to resume classes expires on Monday

The government-imposed deadline for all medical students nationwide to return to classes from mass yearlong leaves of absence is set to expire on Monday, as almost all students at major medical schools in South Korea have already decided to resume their studies.

The March 31 deadline was set by the government early this month, when it announced a conditional decision to place the medical school enrolment quota for 2026 at 3,058, which is equivalent to the figure before the government put forward a plan to increase admissions by 2,000 a year ago to address a chronic shortage of doctors, news agency reported.

The government said the revised quota will be contingent on the return of all medical students who have been boycotting classes and taking collective leaves of absence in protest of the expansion of the medical school quota.

Aerobic exercises, resistance training key to reduce breast cancer recurrence: Study

Aerobic exercises, resistance training key to reduce breast cancer recurrence: Study

Indulging in moderate- to high-intensity aerobic exercises twice to three times weekly, with resistance training added in a few times per week, may potentially reduce the recurrence rate of breast cancer, according to new research.

While aerobic exercises like swimming, running, and climbing stairs, resistance training includes pushups and bench presses.

Researchers from Edith Cowan University (ECU) in Australia said that despite the advances made in breast cancer treatment, recurrence remains common and continues to contribute to higher mortality risks.

In more aggressive cancers, the risk of recurrence can be as high as between 20 per cent and 30 per cent.

Study of cardiac cells in space to help repair heart damage on Earth

Study of cardiac cells in space to help repair heart damage on Earth

A new study of cardiac cells at the International Space Station (ISS) is set to pave the way for repair of the heart damage on Earth.

Researchers from Emory University looked at cancer cells that proliferate -- grow and divide to produce more cells -- much more quickly in microgravity. Spaceflight also triggers cancer cell survival mechanisms, helping the cells better cope with the stressful environment.

In the paper, published in the journal Biomaterials, the researchers hypothesised that heart cells might exhibit similar behaviour.

This would address two current roadblocks in developing cell-based therapies for heart disease, said Chunhui Xu, a professor in the department of paediatrics.

After successfully testing the theory in a ground-based study using simulated microgravity, Xu and her team conducted two spaceflight investigations.

Measles outbreak spreads in US

Measles outbreak spreads in US

The United States is grappling with a significant increase in measles cases, US health authorities have said.

The number of infections in early 2025 has already exceeded the entire 2024 total, according to the latest data from the US Centres for Disease Control and Prevention (CDC).

As of March 28, 2025, the CDC reported 483 confirmed measles cases across 20 states, among them 2 dead and 70 hospitalised, while only 285 cases were reported in 33 states during the entire year of 2024.

Texas is experiencing the most severe outbreak as 400 cases have been identified since late January, and 41 of the patients have been hospitalised, according to the Texas Department of State Health Services.

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