UK researchers have found that one in 3,000 people could be carrying a defective gene that significantly raises their risk of having a punctured lung.
Punctured lung -- known as pneumothorax -- is caused by an air leak in the lung, resulting in painful lung deflation and shortness of breath.
In a study, encompassing more than 550,000 people, researchers from the University of Cambridge discovered that between one in 2,710 and one in 4,190 individuals carry a particular variant of gene FLCN that raises the risk of Birt-Hogg-Dube syndrome.
Birt-Hogg-Dube syndrome is a rare, inherited disorder characterised by benign skin tumours, lung cysts, and an increased risk of kidney cancer. However, not every case of punctured lung is caused by a fault in the FLCN gene.